Has my patient achieved adequate myocardial reperfusion?

For two decades, the goal of reperfusion has been restoration of normal epicardial blood flow.1–4 It has, however, become increasingly apparent that not all TIMI grade 3 flow is created equally, and attention has shifted downstream to the restoration of normal myocardial perfusion to fully optimize clinical outcomes.3,4 The goal of this Clinician Update is to provide clinicians with a better understanding of myocardial perfusion in terms of its importance, assessment, and treatment in clinical practice.